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Chronic overdose of glucocorticoids leads to Cushingoid syndrome, which is clinically identical to Cushing's syndrome. The only difference is that in Cushingoid, the excessive steroids are from drug therapy.

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An increased concentration of glucocorticoids in the blood will?

An increased concentration of glucocorticoids in the blood can lead to effects such as increased blood sugar levels, suppression of the immune system, and reduced inflammation. Chronic elevations of glucocorticoids can also have negative impacts on mental health and lead to conditions like Cushing's syndrome.


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