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The first two things you have to look at are diabetic neuropathy and carpal tunnel syndrome. Diabetic neuropathy is more of a burning pins and needle feeling and can effect the feet as well and of course you would have to have Diabetes. Carpal tunnel syndrome classically will give you numbness and tingling of the first 2 or 3 fingers at night and upon waking. You may have a history of diabetes, hypothyroidism or repetitive use of hands. It effects women 2:1 usually in the 35-55 year old range and unlike diabetic neuropathy it won't effect your feet and it may be in one hand.

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Q: What causes pins and needles sensation in hands after sleeping?
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