What causes transmembrane channels in target cells?
What do scientists currently believe is the cause of Cystic Fibrosis How are the faulty gene inherited and what direct effect does that have on the affected cells?
The faulty gene causes the misfolding of a protein called the Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR is responsible for the movement of chloride and sodium ions into and out of cells. The lack of salt and water on the surface of the cells causes the mucus to become extremely thick and sticky which builds up in and clogs organs.
The protein affected by cystic fibrosis is called the cystic fibrosis transmembrane conductance regulator or CFTR. CFTR acts as a channel that transports negatively charged chloride ions into and out of cells. This helps control the flow of water in tissues. CFTR also regulates the function of other channels that transport positive sodium ions into and out of cells.
In your body, you have certain cells that can receive and process hormones released by your pituitary gland, hypothalamus and other endocrine glands. However, not all cells can receive all hormones. Target cells are cells that have receptors on them for a specific hormone. So a target cell may have a receptor for GH hormone, thus allowing GH to be absorbed by only the target cells with GH receptors.