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ACh binds to each ACH receptor which causes opening of ligand-regulated ion gate and the creation of end-plate potential.
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What is a cholinomimetic agent?
A drug or compound that acts like acetylcholine (ACh). Acetylcholine is a neurotransmitter. In the peripheral nervous system (PNS), acetylcholine activates muscles. In the central nervous system (CNS), acetylcholine tends to cause decreased muscle contractions. These two responses are opposite. ACh Receptor agonists (booster of the effect) are used to treat myasthenia gravis and Alzheimer's disease. ACh receptor antagonists block muscle contractions causing paralysis. The bite of the Black Widow spider does this.
What is the effect of atropine plus acetylcholine on frog heart?
ACh will decrease heart rate/contractile strength, etc. Atropine is a muscarinic ACh receptor (mAChR) antagonist, so blocks the effects of ACh. Adding both together will result in a weak action of ACh that tails off as all the mAChRs become blocked by Atropine.
Which sensory receptor is sensitive to change in tension of a muscle?
proprioceptors
What are cells which detect change called?
They are called Receptor Cells
A deficiency of ACh receptors in a motor end plate would cause and is called?
myasthenia gravis
What statement describes nicotinic acetylcholine ACh receptors as opposed to muscarinic ACh receptors?
Nicotinic receptors are closed until ACh molecules bind to the receptor proteins.
What is a cholinomimetic agent?
A drug or compound that acts like acetylcholine (ACh). Acetylcholine is a neurotransmitter. In the peripheral nervous system (PNS), acetylcholine activates muscles. In the central nervous system (CNS), acetylcholine tends to cause decreased muscle contractions. These two responses are opposite. ACh Receptor agonists (booster of the effect) are used to treat myasthenia gravis and Alzheimer's disease. ACh receptor antagonists block muscle contractions causing paralysis. The bite of the Black Widow spider does this.
Select the option that lists the steps of normal nerve function in the correct order?
ACh is produced at the intercellular level and is stored in vesicles at nerve endings. nerve endings release ACh ACh attavhes to the receptor site at the receiving nerve ACh is broken down by AChE to prevent accumulation
What is the effect of atropine plus acetylcholine on frog heart?
ACh will decrease heart rate/contractile strength, etc. Atropine is a muscarinic ACh receptor (mAChR) antagonist, so blocks the effects of ACh. Adding both together will result in a weak action of ACh that tails off as all the mAChRs become blocked by Atropine.
How many air change require for car parking?
as per design NBC 2005 ( 9 to 12 ACH ) 10 ACH can be consider in case of fire 30 ACH to consider
How would you change the pA2 for a drug-receptor pair?
The only way to change the pA2 would be to alter the nature of the receptor, because the pA2 is essentially a measurement of the affinity of the antagonist drug for the receptor. So, in order to change this value, one would need to change the receptor in a way that changes the binding affinity of the drug.
When a signal molecule binds to a receptor protein the receptor protein may change the?
shape.
What is ACh receptors?
ACH receptors can be defined as an integral membrane protein that responds to the binding of acetylcholine, a neuoyansmitter. Two example are nicotinic acetyl line receptors and muscarinic acetylcholine receptors. .
An allosteric receptor embedded in a cell membrane will change shape only?
when a signal molecule fits the shape of the receptor
Why levodopa can cause postural hypotension?
by di receptor stimulation
Does a receptor detect change in the environment?
yes they do ;) the skin for the temperature :)
Which sensory receptor is sensitive to change in tension of a muscle?
proprioceptors
