because they are tuff
Nitrogenous bases are held together by hydrogen bonds, thus making them easier to separate during DNA replication.
Breaking Hydrogen Bonds.
Helicases must break the hydrogen bonds between paired nucleotide bases (Thymidine-Adenosine or Guanosine-Cytosine) of DNA strands so the two strands can be separated and replicated. The origins of replication, the initial "replication bubbles", tend to be in sequences that are A-T rich because Adenine-Thymidine has only two hydrogen bonds, energetically easier for helicases to start breaking than the three hydrogen bonds between Guanosine-Cytosine. For replication to continue topoisomerases must also cut the phosphate backbones of DNA strands, otherwise the helically wrapped strands would get much too overwound or "supercoiled" for polymerases and related replication machinery to continue to function. Nucleosomes (complexes of histone proteins that DNA wraps around) also have to be rearranged or removed to allow for replication.
DNA helicases break the hydrogen bonds in the DNA molecule
It's the DNA polymerase that catalyzes the formation of phosphodiester bonds between the nucleotides during replication.
hydrogen in bases
By forming matching hydrogen bonds.
Nitrogenous bases are held together by hydrogen bonds, thus making them easier to separate during DNA replication.
The hydrogen bonds are broken in order to unzip the DNA strand. This all occurs during the DNA replication process.
Hydrogen bonds (H-bonds) are broken between the nitrogenous bases when the two strands of DNA separate. These bonds are not as strong as the covalent bonds holding together the sugar and phosphate in the backbone, so the H-bonds break first.
hydrogen bonds
Breaking Hydrogen Bonds.
so that the DNA strands can separate easily during replication.
hydrogen bonds
Hydrogen Bonds
It breaks the hydrogen bonds between the base pairs
In preparation for DNA replication or transcription.