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Renin
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The enzyme renin raises blood pressure by activating the?
renin activates angiotensin in the blood
What does renin activate?
Renin mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure. It activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE. Angiotensin II then constricts blood vessels, increases the secretion of ADH and aldosterone, and stimulates the hypothalamus to activate the thirst reflex, each leading to an increase in blood pressure.
Do the kidneys affect angiotensin II?
Certain kidney disorders increase the production of angiotensin II, another cause of hypertension
What does angiotensin-converting enzyme do?
The primary function of ACE is to help regulate arterial pressure by converting angiotensin I to angiotensin II
What are Angiotensin-converting enzyme inhibitors?
They are medicines that block the conversion of the chemical angiotensin I
What does Serum Angiotensin-Converting Enzyme do?
The primary function of ACE is to help regulate arterial pressure by converting angiotensin I to angiotensin II
What triggers the release of aldosterone?
angiotensin
Does Renin cause a decrease in blood pressure?
No. Renin causes the blood pressure to rise. By low blood pressure the body releases Renin from the kidneys. Renin cleaves an inactive peptide, called Angiotensinogen, converting it to Angiotensin I. Angiotensin I is then converted to Angiotensin II by ACE (Angiotensin-Converting-Enzyme). Angiotensin II causes vasoconstriction and thus an increase in blood pressure.
What are ACE enzymes?
ACE stands for Angiotensin Converting Enzyme. Angiotensin II is the most potent vasoconstrictor in your body. In order to get from Angiotensin I to Angiotensin II, there is an enzyme required for this reaction to occur. ACE inhibitors are used to treat high blood pressure (and congestive heart failure) and they exert their effect by blocking the enzyme.
What are the most potent vasoconstrictors known that are peptides?
Urotensin II, Endothelin, Angiotensin II
Production of angiotensin II indirectly?
raises the blood volume
Do angiotensin II blockers affect preload or afterload?
Afterload
