raises the blood volume
Certain kidney disorders increase the production of angiotensin II, another cause of hypertension
Renin which causes the production of Angiotensin which ultimately is converted into Angiotensin II.
No, Micardis is an ARB (angiotensin II receptor blocker). ACE inhibitors reduce the production of Angiotensin-II, whereas ARBs block them from binding to receptors on cell walls).
The primary function of ACE is to help regulate arterial pressure by converting angiotensin I to angiotensin II
The primary function of ACE is to help regulate arterial pressure by converting angiotensin I to angiotensin II
angiotensin
Renin
No. Renin causes the blood pressure to rise. By low blood pressure the body releases Renin from the kidneys. Renin cleaves an inactive peptide, called Angiotensinogen, converting it to Angiotensin I. Angiotensin I is then converted to Angiotensin II by ACE (Angiotensin-Converting-Enzyme). Angiotensin II causes vasoconstriction and thus an increase in blood pressure.
ACE stands for Angiotensin Converting Enzyme. Angiotensin II is the most potent vasoconstrictor in your body. In order to get from Angiotensin I to Angiotensin II, there is an enzyme required for this reaction to occur. ACE inhibitors are used to treat high blood pressure (and congestive heart failure) and they exert their effect by blocking the enzyme.
Urotensin II, Endothelin, Angiotensin II
Afterload
No, Diovan (valsartan) is an angiotensin receptor blocker (ARB). While angiotensin converting enzyme (ACE) inhibitors prevent the conversion of angiotensin I to angiotensin II, ARBs prevent the angiotensin I from binding to the AT1 receptor. End result is the same, inhibition of vasoconstrictive properties of angiotensin I and reduction in blood pressure.