Madina and Mecca.
Muhammad was involved with both.
There is no specific city that is considered to be in the middle of Islam. Islam is a global religion, with followers and centers of worship located worldwide. The holy cities of Mecca and Medina in Saudi Arabia hold particular significance in Islam, but they are not considered to be in the exact middle of the religion.
Jerusalem
The main religion of the Middle East is Islam.
Islam Islam
Islam
ISLAM is the religion of over 90% of Middle Easterners.
Sunni Islam, Shi'a Islam, Christianity, Judaism, and the Baha'i Faith.
islam is located in the middle east. also islam is mostly desert
Islam.
The city of Mecca and the city of Madina are both holy cities of Islam.
Mainly Islam.
Neither. Islam is a religion.
The dominant religion in the Middle Ages depended on where you were. In most of Europe, it was Christianity, and in the Middle East and North Africa, for most of the Middle Ages, it was Islam. There were places where both were about equally important, such as Spain.