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Ostwald T. Avery's experiment was an extension of the works of Griffith's. Griffith's experiment using virulent and avirulent Streptococcus pneumoniae (which had different colony characteristics) proved that it was possible for the heat killed virulent Streptococcus pneumoniae to pass on the genetic information for formation of smooth colonies to avirulent strains. Avery, Mc Leod and Mc Carty conclusively found out that the genetic material responsible for transfer of characteristics between the strains was DNA. This was achieved by incubating the cell lysate of virulent Streptococcus with proteases, RNAses and DNAses separately before mixing it with avirulent strains. It was found that only when the lysate was incubated with DNAses did the transfer of smooth colony formation characteristic from the virulent strain to the avirulent strain fail to occur.

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14y ago
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12y ago

He discovered that DNA contains a double helix spiral

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13y ago

DNA Was The Transforming Factor, I' Think

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12y ago

Avery's theory provided evidence for knowing that DNA contains the instructions for the making of the capsule in the Sstrain of S. pneumoniate.

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Q: What did Avery's theory provide evidence for?
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