How can a small change in a persons DNA cause a genetic disorder?

Answer 1

Some genes encode products that regulate the translation of other genes, or the activity of other proteins, so one small change will affect a lot of other genes/proteins. If that change affects something critical it might lead to a genetic disorder.

Answer 2

Sure. Single base mutation sometimes results in serious genetic disorder. For example, sickle-cell anemia come about when one base changes. The product,hemoglobins , though with only one amino acid different, would led to aggregation under certain circumstance.

Answer 3

A small change in a person's DNA cause a genetic disorder because changes in a gene's DNA sequence can change the organisms proteins by altering their amino acid sequences, which may directly affect one's phenotype which most likely would result in a genetic disorder.

Answer 4

A small change as in the order of the DNA's processing? This would result in the mitochondrial commands becoming corrupt and creating disheveled cells. Again, this sort of behaviour would result in cancerous or disabled tissues. The DNA processing order is critical to the function of the cell, therefore any sort of damage would result in utter failure.

Answer 5

changes in dna that are inherited or aquired are caused by mutagens which cause mutations, while some mutaions can be benefitful although it can be hard to predict, most of the time the result would be a serious disorder since dna stores information stored in a specific sequnce of nitrogenous bases known as adenine, cytosine, guanine, and finally thymine. the order in which they occur code for proteins which are very important when producing gene expression so if a gene codes for example tyrosine which is a neurotransmitter important for sending messages in the nervous system if a persons dna is mutated or changed so that the code which is uac is changed to uaa then the gene will no be expressed and not making as a result tyrosine which if it is not produced then the person could have some serious mental disability.. who knows what the result would be. hope this helps!!

Answer 6

In both cystic fibrosis and sickle cell disease, a small change in the DNA of a single gene affects the structure of a protein, causing a serious genetic disorder.

Answer 7

Sickle cell disease is caused by a small change in the DNA of a single gene.