There are a number of experts who believe that syphilis is a new world disease, and so would not have existed in medieval Europe, but this theory is disputed by other experts.
Fleas spread the plague
The first answer that comes to mind is the plague.
diseases and wars
black plaguecholeraflusmall pox
That remedy was called the bleeding. It caused the worsening in most patients.
The period of time from 500 AD to 1500 AD is called the Middle Ages.
the impact of the arab empire in the middle ages was that they helped create and learnt about medicine and helped thhe europeans to show them how to create cures for many/various diseases.
There was no explorers in the middle ages. When exploration started that is when the middle ages ended.
The middle colonies had diseases
The third period of the Middle Ages was the Late Middle Ages. The first is called the Early Middle Ages or the Dark Age. The second period was the High Middle Ages.
Early Middle Ages 400 - 700, High Middle Ages 700 - 1300, Late Middle Ages 1300 -1500.
Middle ages