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Chemical breakdown is one of the two types of digestion of food. It is the breakdown of complex molecules to simpler monomers. Chemical digestion takes place in the mouth, stomach, and small intestine of the human body. Enzymes play a major role in chemical breakdown. In the mouth, the enzyme amylase speeds up the breakdown of starch into sugar. In the stomach, gastric protease speeds up the breakdown of proteins to polypeptides and amino acids. Finally, in the small intestine, bile emulsifies fat and pancreatic fluids deliver enzymes such as amylase, protease, and lipase to break down starch, proteins, and lipids into glucose, amino acids, and fatty acids/glycerol respectively. Enzymes are key to the digestion of food.

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