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macula densa cells
macula densa
macula densa
macula densa
The mechanism for maintaining filtration rate in relation to blood pressure is carried out by the juxtaglomerular apparatus which is composed of the macula densa and the juxtaglomerular cells in the kidneys. When blood pressure drops, the juxtaglomerular apparatus secretes renin, which initiates the renin-angiotensin-aldosterone cycle that raises blood pressure.
macula densa cells
Correct Answer: changes in solute content of the filtrate
macula densa
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In the kidney, the macula densa is an area of closely packed specialized cells lining the wall of the distal tubule at the point of return of the nephron to the vascular pole of its parent glomerulus glomerular vascular pole. The cells of the macula densa are sensitive to the ionic content and water volume of the fluid in the tubule. If low water volume is detected by these cells, they will produce molecular signals that promote renin secretion by other cells of the juxtaglomerular apparatus. The release of renin is an essential component of the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and volume. http://en.wikipedia.org/wiki/Macula_densa
macula densa
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macula densa
macula densa
Renin can be upregulated in two ways: Macula densa cells in the early distal tubule of the nephron communicates with the juxtaglomerular cells of the afferent arteriole in the kidney. When the macula densa cells detect low levels of sodium, it will communicate that to the juxtaglomerular cells and in turn that will stimulate the production of renin. This is the glomerular tubular feedback system. The second way it can be stimulated is by the somatic nervous system directly. When the baroreceptors detect a drop in pressure they will stimulate your SNS and inhibit your PNS. This has several cardiovascular effects in addition to stimulating renal nerves that will upregulate more renin from the juxtaglomerular cells.
When the macula densa in the distal tubules of the kidney sense a decrease in fluid volume, the renin-aldosterone system is activated. Aldosterone is the hormone responsible for sodium retention, causing water to be conserved.
Juxtaglomerular cells Visceral and parietal epithelium The above are some specialized cells of urinary system. The cells of the distal tubule become taller and form a structure known as the MACULA DENSA. and this is the specialized tissue in urinary system.