Renin can be upregulated in two ways:
Macula densa cells in the early distal tubule of the nephron communicates with the juxtaglomerular cells of the afferent arteriole in the kidney. When the macula densa cells detect low levels of sodium, it will communicate that to the juxtaglomerular cells and in turn that will stimulate the production of renin. This is the glomerular tubular feedback system.
The second way it can be stimulated is by the somatic nervous system directly. When the baroreceptors detect a drop in pressure they will stimulate your SNS and inhibit your PNS. This has several cardiovascular effects in addition to stimulating renal nerves that will upregulate more renin from the juxtaglomerular cells.
renin
The principal determinant for the release of aldosterone from the adrenal cortex is a decrease of blood pressure in the afferent arteriole.
Renin is synthesized in the juxtaglomerular cells of the Kidney. Renin acts on the liver to synthesize Angiotensin I
Renin.
renin activates angiotensin in the blood
Renin is a protein released by cells in your kidneys when you have low sodium levels. Renin increases the amount of angiotensinogenase increasing blood pressure and renin inhibitors are used to prevent increased blood pressure that can lead to a number of problems.
The renin stimulation test is performed to help diagnose and distinguish the two forms of hyperaldosteronism.
Hypertension (high blood pressure) occurs in cases of excess renin.
by function is enzyme ... by structure is hormone
renin
Heart & brain functions effects blood pressure.
Plasma renin activity (PRA), also called plasma renin assay, may be used to screen for high blood pressure (hypertension ) of kidney origin, and may help plan treatment of essential hypertension