renin
Renin
renin
renin
Juxtaglomerus apparatus
smooth muscle
The juxtaglomerular apparatus is a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning thick ascending limb of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells
Pepsin is a digestive enzyme released by the chief cells in the stomach. It breaks down proteins into smaller fragments to prepare the body for digestion.
Juxtaglomerular cells Visceral and parietal epithelium The above are some specialized cells of urinary system. The cells of the distal tubule become taller and form a structure known as the MACULA DENSA. and this is the specialized tissue in urinary system.
Renin
Juxtaglomerus apparatus
The cells of the juxtaglomerular complex of the nephron. Granular cells in the kidney monitor alteration in blood pressure. If blood pressure falls and remains low, this specialized cells release the enzyme renin into the blood stream.
smooth muscle
Renin is synthesized in the juxtaglomerular cells of the Kidney. Renin acts on the liver to synthesize Angiotensin I
Renin can be upregulated in two ways: Macula densa cells in the early distal tubule of the nephron communicates with the juxtaglomerular cells of the afferent arteriole in the kidney. When the macula densa cells detect low levels of sodium, it will communicate that to the juxtaglomerular cells and in turn that will stimulate the production of renin. This is the glomerular tubular feedback system. The second way it can be stimulated is by the somatic nervous system directly. When the baroreceptors detect a drop in pressure they will stimulate your SNS and inhibit your PNS. This has several cardiovascular effects in addition to stimulating renal nerves that will upregulate more renin from the juxtaglomerular cells.
juxtaglomerular apparatus
The juxtaglomerular apparatus is a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning thick ascending limb of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells
It is made from an enzyme released primarily from cells from the skeletal cavity (cartilage) during growth development.
Pepsin is a digestive enzyme released by the chief cells in the stomach. It breaks down proteins into smaller fragments to prepare the body for digestion.
The mechanism for maintaining filtration rate in relation to blood pressure is carried out by the juxtaglomerular apparatus which is composed of the macula densa and the juxtaglomerular cells in the kidneys. When blood pressure drops, the juxtaglomerular apparatus secretes renin, which initiates the renin-angiotensin-aldosterone cycle that raises blood pressure.
enzyme sped up the chemical reaction