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BRCA1 and BRCA2 are two genes in your DNA which when altered or mutated, leads to Breast cancer.
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∙ 11y ago
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What does BRCA 2 control?
you can figure it out
The BRCA 1 and BRCA 2 mutations increase the risk of which cancer in women?
Yes, but the BRCA1 and BRCA2 tests can also be negative.
What does BRCA stand for?
BRCA1 and BRCA2 are genes that can mutate into cancer.
Where is BRCA testing done?
It's usually done in hospitals.
What mutagen causes breast cancer?
Well the onco genes are BRCA-I and BRCA-II if mutated they cause breast cancer, I think that is what you meant, if not then you may have learned something new anyway
How do the BRCA genes function differently in a person with the mutation?
The BRCA genes are involved in initiating DNA repair and cell cycle check points, they as as regulators of other tumour supressors genes such as p53 and help the cell repair and damage which may lead to cancer occurring in the cell. In mutant versions of the BRCA genes they cannot perform their roles and damaged DNA may cause the cell to replicate uncontrollably as check point to prevent this has been removed. Genome stabiliy is affected and cancer can develop
What is the genetic basis of cancer?
Some cancers show a genetic predisposition - for example BRCA Mutation a form of breast CA.
Is breast cancer disease genetic communicable enviromental oe behavioral?
Breast cancer has a bit of all.The genetic cases only make up around 5% of all cases (check out BRCA 1 and BRCA 2 genes).The environment definitely impacts on it (eg. smoking).I guess behavioral falls into environmental.However, the great majority is just random, that's why it's important to get screened regularly, espacially for women over 40.
Is the test BRCA 12 done at Tata Memorial Hospital If yes what is the cost of the test and what specimen has to be sent and where?
You need to speak to a certified genetics counselor. The test ranges from 300 to 3000 dollars depending on which panel you have done (a cgc can help you decide) There's a website called FORCE (facing our risk of cancer empowered) that is specifically for people with increased risk of breast and ovarian cancer...they can answer just about any question you have abour brca 1 and 2...good luck!
What percentage of breast cancer is down to a genetic fault?
5% of breast cancer is down due to a genetic fault. These genes are passed down through abnormal genes passed from parent to child. An example of this is the BRCA genes.
What is the most common cause for endometrial cancer?
The cause of breast cancer is not fully understood. Heredity or genetically related susceptibility is considered to play a role. Hormonal regulation of the breast is related to the development of breast cancer, but the mechanisms are poorly understood. Sex hormones (like estrogen) may act as a tumour promoters id initiating agents have induced malignant changes. Estrogen doesn't cause Breast Cancer, but the initiating agents that are found in a susceptible person may accelerate its growth. Additional factor under study include physical inactivity, dietary fat intake, obesity, and alcohol intake. Environmental factors such as chemical, pesticide, and radiation exposure may also play a role. Gene abnormalities may be inherited. 5 to 10 percent of all breast cancer persons inherit this gene. Tumour suppressor genes BRCA-1 gene, located in chromosome 17 is a tumour suppressor gene that inhibits tumor development when functioning normally. Women who have BRCA-1 mutations have a 50-85 percent lifetime chance of developing breast cancer. BRCA-2 is another culprit. BRCA tumor suppressor genes mutations may account for 10-40 percent of breast cancers.
What has the author Masha Gessen written?
Masha Gessen has written: 'The man without a face' -- subject(s): Politics and government, Presidents 'Half a Revolution' 'Blood Matters' -- subject(s): Social aspects, BRCA genes, Genetic counseling, Diagnosis, Medical genetics, Human chromosome abnormalities, Social aspects of Medical genetics
