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What else can I help you with?
What DNA mutations are directly linked to inherited diseases?
Some common DNA mutations directly linked to inherited diseases include the CFTR gene mutation in cystic fibrosis, the BRCA gene mutations in breast and ovarian cancers, and the HTT gene mutation in Huntington's disease. These mutations can be inherited from one or both parents and increase the likelihood of developing the associated disease.
What is the cost for BR-CA testing?
The cost for BRCA testing can vary widely depending on several factors, including the laboratory performing the test, geographic location, and whether the patient has insurance coverage. On average, the price for BRCA testing ranges from $300 to $5,000. Many insurance plans may cover the cost if the patient meets certain criteria, such as a family history of breast or ovarian cancer. It's advisable to check with both the healthcare provider and the insurance company for specific costs and coverage details.
Do you all have a brca gene?
Yes we do. There are various estimates, but most experts agree that we produce a few cancer cells on a daily basis. It is our immune system that finds them and destroys them before they get a chance to multiply and cause problems.
BRCA-1 gene in place of an A nucleotide there was the nucleotide that normally pairs with cytosine C. This nucleotide is abbreviated as?
In the context of the BRCA-1 gene, if an A nucleotide is replaced with the nucleotide that normally pairs with cytosine (C), the nucleotide that is substituted is thymine (T). This is because adenine (A) pairs with thymine (T) in DNA, while cytosine (C) pairs with guanine (G). Therefore, the abbreviation for thymine is T.
What does BRCA stand for?
BRCA1 and BRCA2 are genes that can mutate into cancer.
What mutagen causes breast cancer?
Well the onco genes are BRCA-I and BRCA-II if mutated they cause breast cancer, I think that is what you meant, if not then you may have learned something new anyway
What is BRCA-1 mutation?
BRCA1 mutation is a genetic alteration in the BRCA1 gene that increases the risk of developing breast and ovarian cancer. Individuals with a BRCA1 mutation have an increased likelihood of developing these types of cancer compared to those without the mutation. Testing for BRCA1 mutations can help in assessing cancer risk and guiding management options.
What DNA mutations are directly linked to inherited diseases?
Some common DNA mutations directly linked to inherited diseases include the CFTR gene mutation in cystic fibrosis, the BRCA gene mutations in breast and ovarian cancers, and the HTT gene mutation in Huntington's disease. These mutations can be inherited from one or both parents and increase the likelihood of developing the associated disease.
What does BRCA mean?
BRCA1 and BRCA2 are two genes in your DNA which when altered or mutated, leads to Breast cancer.
What is the most common cause for endometrial cancer?
The cause of breast cancer is not fully understood. Heredity or genetically related susceptibility is considered to play a role. Hormonal regulation of the breast is related to the development of breast cancer, but the mechanisms are poorly understood. Sex hormones (like estrogen) may act as a tumour promoters id initiating agents have induced malignant changes. Estrogen doesn't cause Breast Cancer, but the initiating agents that are found in a susceptible person may accelerate its growth. Additional factor under study include physical inactivity, dietary fat intake, obesity, and alcohol intake. Environmental factors such as chemical, pesticide, and radiation exposure may also play a role. Gene abnormalities may be inherited. 5 to 10 percent of all breast cancer persons inherit this gene. Tumour suppressor genes BRCA-1 gene, located in chromosome 17 is a tumour suppressor gene that inhibits tumor development when functioning normally. Women who have BRCA-1 mutations have a 50-85 percent lifetime chance of developing breast cancer. BRCA-2 is another culprit. BRCA tumor suppressor genes mutations may account for 10-40 percent of breast cancers.
Is breast cancer disease genetic communicable enviromental oe behavioral?
Breast cancer has a bit of all.The genetic cases only make up around 5% of all cases (check out BRCA 1 and BRCA 2 genes).The environment definitely impacts on it (eg. smoking).I guess behavioral falls into environmental.However, the great majority is just random, that's why it's important to get screened regularly, espacially for women over 40.
What is the genetic basis of cancer?
Some cancers show a genetic predisposition - for example BRCA Mutation a form of breast CA.
What type of cancer are the Amish prone to?
The Amish community is often observed to have a lower incidence of certain cancers, but they are particularly prone to specific types due to their genetic background and lifestyle factors. For instance, they may have a higher risk of breast cancer, particularly among women, due to genetic predispositions. Additionally, certain familial cancer syndromes, such as those related to BRCA mutations, can also be more prevalent in some Amish groups. Overall, their health patterns are influenced by their unique genetics, lifestyle, and limited access to modern medical care.
How do the BRCA genes function differently in a person with the mutation?
The BRCA genes are involved in initiating DNA repair and cell cycle check points, they as as regulators of other tumour supressors genes such as p53 and help the cell repair and damage which may lead to cancer occurring in the cell. In mutant versions of the BRCA genes they cannot perform their roles and damaged DNA may cause the cell to replicate uncontrollably as check point to prevent this has been removed. Genome stabiliy is affected and cancer can develop
Is breast cancer hereditary?
HereditaryBreast CancerAccording to the National Institutes of Health, breast cancer can be a hereditary condition. However, hereditary breast cancer only accounts for 5%-10% of all breast cancer cases involving inherited gene mutations. Hereditary breast cancers often occur in younger women and involve both breasts. Regardless, when the family history is strong for development of breast cancer, a woman's risk is increased.AnswerThere are tests (BRCA 1,2 and 3) to see if you have a genetic link for breast cancer. However, having one of these marks will not tell if and when you will get breast cancer. There are many other factors for getting breast cancer (estrogen lifetime exposure, alcohol/cigarette use, etc).Men also have a hereditary risk and those with multiply family members with breast cancer histories should be particularly careful to report changes to their physician.It can be. It is possible to inherit mutated BRCA1 or BRCA2 genes that can greatly increase your risk of breast cancer.
What percentage of breast cancer is down to a genetic fault?
5% of breast cancer is down due to a genetic fault. These genes are passed down through abnormal genes passed from parent to child. An example of this is the BRCA genes.
