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The shotgun phase of the Human Genome Project itself consisted of three steps: Obtaining a DNA clone to sequence. Sequencing the DNA clone. Assembling sequence data from multiple clones to determine overlap and establish a contiguous sequence.
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Izaiah Lubowitz
Nellie Bauch
Wiki User
∙ 13y agoWiki User
∙ 15y agoWhat a question. It would fill volumes. However, let me point out that the human genome is a project involving almost every civilized nation in the world. We raced to have the ability to spell it out ... and it only can be spelled with four letters. AGCT are the only letters in the alphabet. And along the way we discovered a many codes. One coded these letters to 20 different other codes. We found a machinery in the cell that took sequences of genomic DNA nucleotides and coded them into proteins. And these proteins are the enzymes, hormones, and other large protein molecules that move throughout the body -- a literal highway of informatics. The question really is -- what is the genome to us at this moment and how did we come to understand it? There is so much more to discover. It is like climbing a mountain and we keep seeing new vistas.
If you want to be an explorer then this is one journey for you!
But let me begin with a few milestones and give you site (a website, that is) to explore more -- Milestones from the Understanding the Human Genome site: http://www.genome.gov/25019887
1800s Darwin expores variation in species from around the known world
Mendel in his own garden discovers laws of inheritance through color of peas
1900s Wilhelm Johannsen coins the term -- a gene for inheritance
1940s One gene appears to code for one enzyme
1950s Genes are made of DNA
Crick and Watson tease out a double helix pattern ... swirling in DNA
1960s Messenger traffic discovered from the genome
The DNA code is finally cracked ... it makes up proteins
1970s Recombinant DNA discovered
First animal gene cloned
DNA Sequencing becomes possible
1980s Maps of the Human Genome appear
Polymerase Chain Reactions simplify DNA amplification and discovery
Powerful techniques to clone and tag DNA discovered
First Diseased Gene Discovered
1990s Human Genome Mapping begins ... with many other genomes along the way
Read about it and enjoy.
Wiki User
∙ 10y agoHuman Genome Sequencing involves taking a sample of Human Tissue, such as a cheek swab where a cotton swab is run across the inside of the mouth against the soft tissue to collect a small sample of the skin cells on the inside of the cheek. After a sample is acquired, it is then broken down using a solution of chemicals to separate the DNA from the sample. The DNA is then broken down further using another solution, and the DNA is run over a special plate where the DNA attaches itself to markers that match it's specific DNA sequences.
Wiki User
∙ 14y agothree major steps in the process of sequencing the humane genome
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Which organization finally finished sequencing the human genome first?
Celera
What did Craig venter discover?
he worked on sequencing the human genome and he went into the sea and sampled the microorganisms
How can bacteriophage contribute to the host genome?
Scientists had already reached the milestone of fully sequencing their first genome that of the FX174 bacteriophage, whose 5,375 nucleotides had been determined in 1977 (Sanger et al., [ 1977b) but this endeavor proved much easier than sequencing the genomes of more complex life forms. Indeed, the prospect of sequencing the 1 million base pairs of the E. coli genome or the 3 billion nucleotides of the human genome seemed close to impossible. ..............
How is the base composition of the DNA of an organism measured?
by sequencing its genome
What goal of the human genome has been achieved?
To map & sequence all of the DNA base pairs of the human chromosomes.
The what has succeeded in sequencing all human chromosomes?
The Human Genome Project
Which organization finally finished sequencing the human genome first?
Celera
What are the benefits of automated DNA sequencing?
DNA sequencing enables the scientists to determine genome sequence. Human genome projects is the biggest example of DNA sequencing. When the human genome was sequenced back in 2001, many issue rose but now after many years, we can see it's impacts on medical and pharmaceutical research.
What innovations in technology have made the Human Genome Project possible?
DNA sequencing.
What does the sequencing of all 3.2 billion nucleotide bases on all human chromosomes describe?
the human genome
What did Craig venter discover?
he worked on sequencing the human genome and he went into the sea and sampled the microorganisms
How are computers used in mapping the human genome?
Computers are needed mainly after sequencing has already been done. Genome sequencing first breaks down the whole genome into small pieces which are sequenced independently. In order to rearrange all the pieces is the correct order computers with powerful statistical programs are used.
How can bacteriophage contribute to the host genome?
Scientists had already reached the milestone of fully sequencing their first genome that of the FX174 bacteriophage, whose 5,375 nucleotides had been determined in 1977 (Sanger et al., [ 1977b) but this endeavor proved much easier than sequencing the genomes of more complex life forms. Indeed, the prospect of sequencing the 1 million base pairs of the E. coli genome or the 3 billion nucleotides of the human genome seemed close to impossible. ..............
What are the release dates for DNA Transistor The Future of Genome Sequencing - 2009?
DNA Transistor The Future of Genome Sequencing - 2009 was released on: USA: 5 October 2009 (internet)
Where can one find information regarding whole genome sequencing?
If you have an interest in gene sequencing it would be a good idea to go take a medical course. Some of the places to learn would be a local college or a technical school. Might even be able to do it online.
How is the base composition of the DNA of an organism measured?
by sequencing its genome
What can be found at the UCSC Genome website?
The UCSC Genome website contains the sequencing information for several genomes. Scientist are continuously sequencing different organisms, and this website is a compilation of that information in a usable format.
