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USP stands for United States Pharmacopeia, which is a company that catalogs the use and side effects of most prescription and over the counter drugs. They publish a book, which is basically the dictionary of pharmaceuticals; your Local Pharmacy probably sells it.

Vitamins and other supplements with a USP label have been put through testing by the United States Pharmacopeia, and have met their minimal standards. It doesn't mean other supplements are not as good (they all need to pass the FDA) but it is another standard that they have succeeded in meeting.

USP is, basically, simply a grade of purity. It means the compounds with that label meet specific criteria regarding "contaminants". It doesn't mean it's either safe or effective for any particular use, just that it's (relatively) pure. For example, you can purchase USP grade hydrochloric acid, but it would be a bad idea to drink it. On the other hand, an ingredient extracted from a plant might not be USP grade because it contains substances other than the primary ingredient, but that doesn't mean those other substances are harmful.

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Q: What does the USP on vitamins bottle mean and without this acronym are the vitamins any good?
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