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hemopholia is caused by a mutation of ones of the genes thatproduces blood-clotting proteins.

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Q: What exactly is happening at the cellular level to cause thise disorder of hemophilia?
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What are a woman chance of being a carrier for hemophilia if she phenotypically a normal woman and has phenotypically normal parents but has a hemophiliac brother?

She has 1/2 chance. We can figure out exactly what her parents' genotypes were. Her brother has a Hemophilia allele that he got from his mom. So their mom has at least 1 Hemophilia allele. If she had 2 then she would have Hemophilia. The father cannot have a Hemophilia allele because it would have been expressed. So her chances are 1/2 because her mother has 1 Hemophiliac and 1 normal allele.


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