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is a molecule inside a cell
true
I'm assuming you're asking what would happen if a receptor did not bind the proper hormone. The answer is a complex one because binding to a receptor does not necessarily mean that the receptor will be activated. Sometimes binding causes receptor inhibition; other times it can mean that the properties of the receptor change so that other hormones have an easier/harder time binding and activating it. But for the sake of giving an answer, let's say that we want to know what happens if a hormone binds and activates the wrong receptor. That answer is a relatively simple one: in most cases, the same events would take place that normally happen when the correct hormone binds the receptor. Let's take an example of a relatively uncommon cause of hypertension called hypertension exacerbated in pregnancy. In this condition, there's a mutation in the receptor for the hormone aldosterone that allows other hormones besides aldosterone (eg, progesterone) to bind it and activate it. When progesterone levels are high, as in pregnancy, the extra progesterone binds and heavily activates the aldosterone receptor, and the receptor essentially "thinks" that aldosterone has bound. So the action of progesterone at the aldosterone receptor are the same as aldosterone itself; since aldosterone is a major contributor to blood pressure, blood pressure increases to very high levels.
Hormones do not bind to receptors with high capacity. The major defining properties of a hormone-receptor interaction, and what determines the strength of response is binding affinity and efficacy.
Target cells respond to hormones because they have specific receptors for the hormone on their cell membrane or inside the cell. These receptors enable the hormone to bind and initiate a cellular response. Other cells that do not have the specific receptors for that hormone are unaffected because they cannot bind to the hormone or activate the necessary signaling pathways.
A mutation in the DNA binding domain of a steroid hormone receptor is most likely to affect the receptor's ability to bind to specific DNA sequences known as hormone response elements (HREs). This can impair the receptor's ability to activate or repress target genes and disrupt the normal functioning of the steroid hormone signaling pathway.
yes a ligand is anything that can change the conformation of a receptor protein. hormones bind to proteins in the same way ligands do
Nitric oxide does not bind to a plasma membrane receptor.
The molecule that can bind to a receptor protein is called a ligand.
each hormone receptor only binds to one hormone
Depending on what harmone it is, the hormone will attach to the receptor protein if the shape of the hormone and the receptor protein correspond.
The cell membrane contains the membrane proteins that enable a hormone to selectively bind to its plasma membrane. These proteins, such as receptor proteins, are responsible for recognizing and binding to specific hormones, allowing the hormone to exert its effects on the cell.