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A red blood cell placed in a hypotonic solution?
This is not true. An isotonic solution is one that is equivalent in concentration to that found within human plasma so that is usually desirable. On the other hand, a person may have too little of an ion. In that case the amount needs to be replaced using a hypertonic solution. The trouble with that is that if the patient is not carefully monitored, too much of whatever ion is used will enter the cells, causing the cells to draw more water in to maintain balance. When that happens, especially with sodium, the patient must be monitored closely because giving too much can cause the sodium level in the cells to exceed normal levels. When that happens, the cells draw more water in which can cause the cells to swell and then the membranes to begin to leak such as we see with pulmonary edema.
What are the Tonicity of the cell?
Cells can be placed in solutions with higher, lower, or equal concentration to the cell... 1. ISOTONIC: - a solution with equal concentration to the cell. - 0.9% NaCl solutions is isotonic to RBC (red blood cells). - isotonic solutions cause no net gain or loss of water to a cell. 2. HYPOTONIC: - solute concentration is greater on the inside of the cell (or: the outer solution has less concentration than inside). - >0.9% NaCl solutions is hypotonic to RBC (red blood cells). - causes swelling, could burst (lyse) - net gain of water 3. HYPERTONIC: - <0.9% NaCl solutions is hypertonic to RBC (red blood cells). - net loss of water from the cell. - solute concentration is greater on the outside of the cell (or: the outer solution is greater concentration than the inside). - causes the cell shrink (crenation in RBC)
What happens if RBC is kept in hypertonic solutino?
If red blood cells (RBCs) are kept in a hypertonic solution, water will move out of the cells due to the higher concentration of solutes outside the cells. This causes the cells to shrink and crenate, leading to potential damage and dysfunction of the RBCs.
What happens if rbc's and saline solutions are mixed?
If red blood cells (RBCs) are mixed with a saline solution, the RBCs may undergo hemolysis, where they rupture and release their contents into the solution. This can lead to changes in the osmotic balance and potentially cause damage to the RBCs. It is important to handle RBCs carefully to prevent hemolysis and maintain their function.
What would be the effect on red blood cell that 10 percent glucose solution would have?
That depends on the concentration of glucose inside of the red blood cell (RBC). If the glucose concentration inside the cells is less than the concentration outside the cell, then water will pass through the cell's membrane and into the surrounding fluid. If the concentration inside the RBC is greater than that of the outside solution, then the RBC will taken in water. Most likely, this will cause the cell to lyse open (burst) and die.
Erythrocytes show various form of haemolysis in a hypotonic solution?
rbcs usually becomes swollen or haemolyse in hypotonic solution, this is due to osmosis. In this case, the concentration of solute is more inside the rbc, hence it exerts osmotic pressure which draws water from lower osmotic solution. The rbc swells to its limit because of its biconcave structure and burst after crossing its limit (haemolysis)
What happens when we place RBC in hypo-tonic solution?
When red blood cells (RBCs) are placed in a hypotonic solution, water moves into the cells due to a higher concentration of solutes inside the cell. This causes the cells to swell and potentially burst, a process known as hemolysis.
If a cell lives in hypotonic environment what will happen if placed in hypertonic environment?
If a cell is used to living in a hypotonic environment, that means that there exists less solute concentration outside of the cell. Take, for example, a red blood cell (RBC). When the RBC is placed in distilled water, the RBC is hypertonic to the water. The water is hypotonic to the RBC. In this case, the RBC will swell, and in most cases rupture. However, if one were to put an RBC in very salty water, the RBC would be hypotonic to the salt water. The salt water would be a hypertonic environment. In this case, the water would diffuse out of the RBC, causing it to shrivel. Awigman
A red blood cell placed in a hypotonic solution?
This is not true. An isotonic solution is one that is equivalent in concentration to that found within human plasma so that is usually desirable. On the other hand, a person may have too little of an ion. In that case the amount needs to be replaced using a hypertonic solution. The trouble with that is that if the patient is not carefully monitored, too much of whatever ion is used will enter the cells, causing the cells to draw more water in to maintain balance. When that happens, especially with sodium, the patient must be monitored closely because giving too much can cause the sodium level in the cells to exceed normal levels. When that happens, the cells draw more water in which can cause the cells to swell and then the membranes to begin to leak such as we see with pulmonary edema.
What is the effect of isotonic salt solution on rbc?
Iso means same, therefore the salt solution concentration is the same as the concentration of salt within the blood cells. So nothing happens - the RBC's remain the same (no shrinking/crenating or swelling/lysing)
What are the Tonicity of the cell?
Cells can be placed in solutions with higher, lower, or equal concentration to the cell... 1. ISOTONIC: - a solution with equal concentration to the cell. - 0.9% NaCl solutions is isotonic to RBC (red blood cells). - isotonic solutions cause no net gain or loss of water to a cell. 2. HYPOTONIC: - solute concentration is greater on the inside of the cell (or: the outer solution has less concentration than inside). - >0.9% NaCl solutions is hypotonic to RBC (red blood cells). - causes swelling, could burst (lyse) - net gain of water 3. HYPERTONIC: - <0.9% NaCl solutions is hypertonic to RBC (red blood cells). - net loss of water from the cell. - solute concentration is greater on the outside of the cell (or: the outer solution is greater concentration than the inside). - causes the cell shrink (crenation in RBC)
What will happen when rbc kept in 10 percent glucose solution?
When red blood cells are placed in a 10% glucose solution, they will undergo crenation, which is the shrinking and deformation of the cells due to water loss through osmosis. The hypertonic solution causes water to move out of the cells, resulting in the cells losing their normal shape and structure.
Name of RBC diluting fluid?
Gower's solution
What does low osmotic fragility means?
Osmotic fragility usually (unless otherwise mentioned) refers to the ease with which Red Blood Cells (RBCs) undergo lysis in a hypotonic solution. Before knowing what 'low osmotic fragility' means, one should know the concept of osmotic fragility. Different parameters, some of them related to the RBC and some of the extracellular environment have an effect on osmotic fragility. Low osmotic fragility means that the RBCs have a resistance against undergoing lysis when suspended in solutions which are hypotonic. They undergo lysis only if the solution is extremely hypotonic. In contrast, high osmotic fragility refers to the tendency of the RBCs to lyse even if the solution in which they are suspended in is mildly hypotonic. As an example for low osmotic fragility would be thalassemia. And as an example for high osmotic fragility, spherocytosis (a hereditary condition where the RBCs lose their usual biconcave structure and become spherical) causes increased osmotic fragility. i.e, It very easily lyses even at solutions which are mildly hypotonic... p.s Another interesting point to note is that in sickle cell anemia, the RBCs show increased mechanical fragility but decreased osmotic fragility. Elucidated by the fact that post-splenectomy the RBC lifespan increases.
What happens if RBC is kept in hypertonic solutino?
If red blood cells (RBCs) are kept in a hypertonic solution, water will move out of the cells due to the higher concentration of solutes outside the cells. This causes the cells to shrink and crenate, leading to potential damage and dysfunction of the RBCs.
Why to use RBC diluting fluid for counting?
You can use any isotonic solution like Normal Saline Solution (NSS), Hayem's and Gower's.
What happens to red blood cells when exposed to high altitude?
The number of RBC will increase
