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What happens if I have too much glucagon?Rare tumours of the pancreas called glucagonomas can secrete excessive quantities of glucagon. This can cause Diabetes mellitus, weight loss, venous thrombosis and a characteristic skin rash. What happens if I have too little glucagon?Unusual cases of deficiency of glucagon secretion have been reported in babies. This results in severely low blood glucose which cannot be controlled without administering glucagon.

Glucagon can be given by injection to restore blood glucose lowered by insulin (even in unconscious patients). It can increase glucose release from glycogen stores more than insulin can suppress it. The effect of glucagon is limited, so it is very important to eat a carbohydrate meal once the person has recovered enough to eat safely.

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Q: What happens if the body produces too much glucagon?
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