An acyltransferase is a transferase enzyme which catalyzes the transfer of acyl groups between lipids.
An aminoacyltransferase is an acyltransferase enzyme which acts upon an amino group.
Fortunato Manganaro has written: 'Purification and characterization of monoacylglycerol acyltransferase from rat intestinal mucosa'
Acetyl glycine is synthesized by combining glycine with acetyl-CoA in a reaction catalyzed by the enzyme glycine N-acyltransferase. This enzyme transfers the acetyl group from acetyl-CoA to the amino group of glycine to form acetyl glycine.
Neutral fat synthesis, also known as triglyceride synthesis, involves the condensation of glycerol with three fatty acid molecules. This reaction is catalyzed by the enzyme glycerol-3-phosphate acyltransferase, which adds the fatty acids to the glycerol backbone to form a triglyceride molecule. This process occurs in the cytoplasm of cells and is an important step in storing energy for future use.
The reaction that binds three fatty acids to a glycerol molecule is called esterification. In this process, each fatty acid reacts with one of the hydroxyl (-OH) groups on glycerol, releasing a molecule of water (H₂O) for each bond formed. This results in the formation of triglycerides, which are a major form of stored energy in animals and plants. The reaction is facilitated by the enzyme acyltransferase.
The carnitine shuttles help transport fatty acyl coA from the cytosol of the cell into the mitochondrial matrix. The acyl group is first transfered to a carnitine and it is catalyzed into fatty acyl-carnitine by carnitine acyltransferease I at the outer mitochondrial membrane. The fatty acyl-carnitine then moves through the intermembrane space of the mitochondria through the transporter carnitine-acylcarnitine translocase. When the acyl group reaches the matrix, it is transferred to mitochondrial CoA, it is catalyzed by carnitine acyltransferase II to reform fatty acyl CoA. The carnitine is regenerated and it moves back to the intermembrane space with the aid of the same transporter.
The cell membrane is a lipid bilayer, composed of phopholipids: A glyerol molecule with two fatty-acid groups at one end and a phosphate group at the other.Phospholipids are synthesised in the cytoplasm next to the endoplasmic reticulum. The ER sythesthies the lipids, and contains enzymes that catalyse the production of phopholipids such as Glycerol-3-phosphate acyltransferase. The phospholipids produced migrate naturally to the internal face of the membrane, and flippase moves them to the outer face.