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The goal of area normalization is to correct for sample size discrepances, that in a negative way affects the sum of all measured solutes.

Example

If 4 peaks are being measured and the sum total area of all peaks turns out

to be less than or greater than 100 percent, Normalization corrects for this

and shifts all peaks by the needed percentage to bring them to a sum of 100

percent. If the sum total equals 90 percent, then normalization will shift up

each individual peak 10 percent, which will bring the sum up to 100 percent..

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Q: What is definition of area normalisation method in HPLC?
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