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What is fatty acid synthesis?

Updated: 10/25/2022
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Greenr1981

Lvl 1
14y ago

Best Answer

Fatty acid synthesis is effectively the reverse of degradation process.

The final synthesized product is a polymer, and hence obviously the process is initiated with the collecting of monomers together.

Considering the case of an activated acyl group and malonyl units, the malonyl unit is condensed with the acetyl unit and results in the formation of a four-carbon fragment. The carbonyl is reduced in order to produce the required hydrocarbon chain. The process will proceed exactly opposite to that of degradation process.

[Activated acyl group (monomer) + Activated malonyl group (monomer) ]

Condensation

Reduction

Dehydration

Reduction

Activated acyl group (polymer with additional two carbon atoms)

The resulted four-carbon fragment will be reduced, dehydrated, and reduced again for carrying the carbonyl group to the level of a methylene group along with butyryl CoA formation.

Also, another activated malonyl group condenses with the butyryl unit and the process will continue until a C16 fatty acid is synthesized.

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