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Why would DNA polymerase drugs be useful against cancer?
Hall mark of cancer is genomic instability, in form of mutations or chromosomal aberrations. Genomic instability is failure to maintain genome stable, which was maintained by using proper replication and repair,any imbalance in this can lead to instability. There are many error prone DNA polymerases which are error prone which were evolved to keep cell alive by continuing DNA replication when extensive DNA damage happened. Many cancers have differential expression of various DNA polymerases Example: Up regulation of DNA polymerase theta in Breast cancer
When was Genomic Standards Consortium created?
Genomic Standards Consortium was created in 2005.
When was Genomic Medicine Institute created?
Genomic Medicine Institute was created in 2005.
What is a map of the distribution of cloned genomic DNA from genomic clone libraries?
physical map
What phase in the cell cycle is likely to be dramatically shorter in a cancer cell?
The pathway controlling G1-phase growth arrest is commonly altered in cancer cells, allowing cancer cells to divide despite shortened telomeres, which can lead to the genomic instability seen in malignant cells
What do you mean by genomic in situ hybridisation technique?
Genomic In Situ Hybridization refers to use of total genomic DNA from one species as a probe for in situ hybridization to identify chromosomes, chromosome segments, or whole genomes originating from that species in a hybrid or backcross.
Where does genomic DNA present in a tissue?
In the mitochondria
What is the TIGR database?
The Institute for Genomic Research
How is a genomic library produced?
A genomic library is produced through the meticulous accumulation of genetic information that lends to different classifications and structures to the level of taxonomy.
What is use of Genomic library?
cloned genes -sarahhh(:
How much percentage of genomic DNA is active?
kk
How do you use the word instability in a sentence?
The instability of a moving platform is often difficult to balance upon.
