depending on where you start and stop in those two states: West Virgina, Virginia, or Pennsylvania
knoxville,tenn
Rawley Springs, Virginia is halfway between Wayne and Kodak
Stanfordville, NY is roughly halfway between Somers and Troy
Memphis, tenn
Nashville tenn
Harmon, NY is halfway between Bronx & Fishkill
Saugerties, NY
newberry Sc
Birmingham, AL.
The halfway point between Lewistown, PA and Albany, NY is Youngmann Memorial Hwy, Buffalo, NY 14228.
Southfields, NY
The halfway point is somewhere around Milepost 52 on I-88, just west of Oneonta, NY.