This is a gradual progressive disease of the spinal cord usually caused by infection with the human t-cell lymphotropic virus. The symptoms of this virus include Back pain with gradual loss of motor functions in one or both legs, ataxia, and urinary incontinence.
Tropical spastic paraparesis (TSP) is a slowly progressive spastic paraparesis caused by the human T-cell lymphotropic virus-1 (HTLV-1), with an insidious onset in adulthood.
The disease may remain undetected for years after infection is contracted.
Hereditary spastic paraplegia (HSP) is a hereditary degenerative disorder affecting the corticospinal tracts (long never fibers that supply the upper and lower limbs) within the spinal cord.
While the disease is incurable, significant improvement has been reported in the condition of TSP patients treated with corticosteroids
isolated cases have been diagnosed in the southeastern United States and other places in the United States
TSP is most frequently found in: the Caribbean, Japan, the Seychelles Islands, regions of South America, western Africa
Infectious disease specialists use blood tests and magnetic resonance imaging (MRI) of the spinal cord to diagnose this condition.
TSP usually affects adults between the ages of 30 and 40, and is far more common in women than in men.
Physical therapy is designed to help restore and maintain useful movements or functions and prevent complications such as frozen joints, contractures, or bedsores.
20% of patients with TSP may also experience: deafness, double vision, dysmetria, exaggerated reflexes, facial paralysis, tremor.
The cause of HAM/TSP is still a matter of debate. Three hypotheses are considered by scientists as the most likely cause of TSP: direct toxicity, autoimmunity, and bystander damage.
significant improvement has been reported in the condition of TSP patients treated with corticosteroids. These drugs are believed to alleviate symptoms by suppressing the immune system's response to the virus that causes them.