Idiotypic antigens are clearly defined tumor-associated protein antigens, which can induce protective immunity against lymphoma. Because each patient requires an individual vaccine, idiotypic antigens also provide ideal candidates for exploring the feasibility of replacing protein antigens by DNA vaccines. Component idiotypic variable region genes can be identified in patients' tumor biopsies and rapidly assembled as scFv sequences. These can be used to produce recombinant scFv protein in bacteria, or as direct naked DNA vaccines. A preliminary small trial of DNA vaccines for chemotherapy-resistant patients with lymphoma has begun. Intramuscular idiotypic DNA vaccination in a mouse model induces low levels of anti-idiotypic antibody in serum. Levels can be increased dramatically by co-injection of DNA plasmids encoding either IL-2 or GM-CSF, and specific proliferative anti-idiotypic T cells are induced. However protective immunity remains to be demonstrated, and a possible reason for this may lie in the continued secretion of idiotypic scFv antigen which blocks antibody activity by formation of immune complexes. Methods for regulating secretion of antigen are required before this category of tumor antigen can be fully exploited as a vaccine. The power of DNA technology should allow analysis and manipulation of pathways of antigen presentation to induce maximal therapeutic attack on neoplastic B cells. In addition, lymphoma presents a model for application of DNA technology to the wide range of human tumors known to harbor potential tumor antigens.
There are many types of technology. These include food technology, educational technology, vehicle technology, electronics, as well as media technology.
wireless technology
It is a fairly new technology.
Bluetooth 4.0 is the latest technology of Bluetooth. It is a low energy technology.
FIber Technology is used in many things: i.e. Telecom Technology Internet Technology Communication technology
Bio Technology Electrical Technology Electronics Technology Fluid Technology Materials Technology Mechanical Technology Optical Technology Structural Technology Thermal Technology
Communication Technology Production Technology Transportation Technology Bio Technology
nanotechnology computer technology medical technology
That depends on the technology you are talking about (e.g. metal casting technology, stone carving technology, heavy construction technology, automobile technology, electronics technology, nuclear technology, irrigation technology, fire fighting technology, submarine technology, painting technology, airplane technology, firearms technology, and even computer related technologies) as the skills requirements vary dramatically.
There are six types of technology. 1.Information technology. 2.Assistive technology. 3.instructional technology. 4medical technology. 5.technology of productivity. 6.technology of teaching.
Yes it is a technology
There are many types of technology. These include food technology, educational technology, vehicle technology, electronics, as well as media technology.
RankInstituteState1Indian Institute of Technology BombayMaharashtra2Indian Institute of Technology KanpurUttar Pradesh3Indian Institute of Technology DelhiDelhi4Indian Institute of Technology MadrasTamil Nadu5Indian Institute of Technology KharagpurWest Bengal6Indian Institute of Technology RoorkeeUttarakhand7Indian Institute of Technology GuwahatiAssam8Indian Institute of Technology RoparPunjab9Indian Institute of Technology HyderabadAndhra Pradesh10Indian Institute of Technology BhubaneshwarOrissa10Indian Institute of Technology PatnaBihar10Indian Institute of Technology GandhinagarGujarat10Indian Institute of Technology IndoreMadhya Pradesh11Indian Institute of Technology JodhpurRajasthan12Indian Institute of Technology MandiHimachal Pradesh
Yes it is a technology
wireless technology
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