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What is lipophilic?

Updated: 4/28/2022
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15y ago

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Lipophilic is a substance that dissolves in or mix consistently with lipids.

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Q: What is lipophilic?
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Is an ionized drug more lipophilic or less lipophilic?

An unionized drug tends to be lipophilic (and hence, would be hydrophobic). Thus, an ionized drug on the other hand would be lipophobic (i.e. the opposite of lipophilic), lipid-hating.


What is the nature of solute?

the nature of interaction depends on whether they are lipophilic or hydrophilic. if both are hydorphilic ionic interaction, both lipophilic hydrogen bonding. ionic if lipophilic-hydrophilic.


What is the nature of solute-solvent interaction?

the nature of interaction depends on whether they are lipophilic or hydrophilic. if both are hydorphilic ionic interaction, both lipophilic hydrogen bonding. ionic if lipophilic-hydrophilic.


What kinds of drug need to be lipophilic?

Drugs which are administered percutaneously, sublingually, or have to cross the blood brain barrier have to be lipophilic.


Why is Xenon lipophilic?

Yes. Xenon is lipophilic and exhibits affinity for cavities in macromolecular interiors. Xenon's lipophilic behavior has been shown from its partition with long-chain hydrocarbons and from its in vitro and in vivo partition with fatty tissue.


Can you explain hydrophilic lipophilic?

Hydrophilic means something that is attracted to or absorbed by water. Lipophilic is something that is attracted to or absorbed by fat.


Are steroids lipophilic?

Yup. They sure are.


Which pesticides are most lipophilic?

Lipophilic pesticides are those that are soluble in the fatty tissues of animals such as fish and people. DDT is the main pesticide with this quality.


What are the differences between 'lipophilic' and 'hydrophobic'?

they are the same.


What is the definition of lipophilic?

Having an affinity for or capable of dissolving in lipids.


Why is drug metabolism needed?

Drug metabolism is needed is lipophilic drugs cannot be cleared renally. These lipophilic drugs need to be metabolised into more polar products so that they can be excreted in the urine.


Why are lipophilic viruses easier to kill?

Lipophilic viruses require the lipid (fatty) envelope to remain active ("live"*), and the fatty layer can be destroyed by alcohol. Non-lipophilic viruses do not require this fatty envelope, and the protein layer (capsid) is more resistant to alcohol. *Note: viruses are not actually alive, they are only genetic codes with 1 or 2 (lipophilic) protective layers. Biologists call "live" viruses *active* and "dead" viruses *inactive* or *inactivated*.