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Q: What is one difference between tracing the inheritance of autosomal traits and tracing the inheritance of sex-linked traits?
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What information on a pedigree can tell yo whether a gene is on autosome or on a sex chromosomes?

You can tell by the patterns and, to a lesser extent, ratios of trait inheritance. Both sex-linked and autosomal traits can be dominant or recessive and the patterns for each type are different. Usually for autosomal inheritance there isn't a difference in the ratios between males and females affected with the trait while in sex-link inheritance there is. If there are traits that seem to skip a generation then they usually are recessive. Genes that are located on the Y chromosome are passed from father to son, never to daughter whereas genes on the X chromosome can go to both. It's important to know that since normal human males only have one X, X-linked traits will be dominant for them whereas for females the trait can manifest in one dose (haplosufficiency) or would have to be in two doses (both X's would have to have the gene).


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