How can you avoid buildup of positive pressure when reconstituting antineoplastics?
There are two ways to avoid positivepressure.1. The first way is to allow air to escape from the vial atthe same time you inject a drug or diluent. Inject smallamounts, little by little, and allow the air from the vialto enter the syringe.2. The second way to prevent aerosolization of drug is touse a chemo safety pin. These pins prevent a drug from leaving by positive pressure. Spike the pin into the drug vial. Thepressure will escape into the pin area rather thanthrough the needle. You'll filter out any aerosolizeddrug in the diaphragm of the chemo safety pin.