Marker for Widal Test carried out for the detection of Salmonella
You can differentiate between different salmonella strains using serology. Each strain has its own combination of antigens. Depending on the O, H, and vi antigens, you can determine which strain is present. The O-antigen is the somatic polysaccharide antigen, the H-antigen is the flagellar antigen and the vi-antigen is the capsular antigen. Antibodies to most of the variants of these antigens are available commercially for use in labs. Adding an aliquot of specific antisera to a suspension of your salmonella spp, and incubating it for a few hours in a water bath will result in visible agglutination if your salmonella strain possesses the specific antigen to the antibody you added. For example, Salmonella typhi will show agglutination with O [9,12], H [d] and vi.
S Typhi H is an antigen associated with Salmonella Typhi, the bacterium responsible for causing typhoid fever. This antigen is used to detect the presence of antibodies in a person's blood, indicating a past or current infection with Salmonella Typhi.
In a Widal test, "H" refers to the flagella antigen of Salmonella typhi while "O" refers to the somatic antigen of the bacteria. The presence of antibodies against these antigens indicates a recent or current infection with Salmonella typhi, the bacterium that causes typhoid fever.
The ABO phenotype that contains the most H antigen on the red cell surface is the O phenotype, as individuals with this phenotype have the highest concentration of H antigen and lack A and B antigens. Conversely, the AB phenotype contains the least H antigen because it has both A and B antigens, which are produced by the modification of H antigen, resulting in a lower amount of unmodified H antigen on the surface.
The default range for Salmonella typhi H (flagellar antigens) and O (somatic antigens) typically refers to the dilution ranges used in serological testing to detect specific antibodies in a patient's serum. Generally, the H antigen is tested at dilutions ranging from 1:40 to 1:320, while the O antigen is tested at dilutions that can vary but often starts around 1:20. These ranges can be adjusted based on specific laboratory protocols or patient conditions. However, it's important to consult specific laboratory guidelines for precise testing parameters.
you might be suffering from typhoid fever as o antigen more than 100 and h antigen more than 200 are significant consult your doctor immediately for proper treatment dr.mahwash
In the treatment of typhoid fever, caused by Salmonella typhi, antibiotics such as ciprofloxacin, azithromycin, or ceftriaxone are commonly used for the O and H antigen strains. The choice of antibiotic may depend on local resistance patterns and the severity of the infection. Supportive care, including hydration and nutritional support, is also essential. Vaccination can help prevent typhoid fever, but it is not a treatment.
It helps to separate blood types
The H is 1. the antigen in the flagella of motile (moving) bacteria; important in serologic classification of enteric (intestinal) bacteria. 2. the chemical precursor of antigens of the ABO blood group locus. Some are very rare types seen in only a few types. It is called "Oh" and also the Bombay (now the city Mumbai) Group.
Antigens.
The Latin name for Salmonella is Salmonella enterica.
Yes.