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it is standard practice that patients presenting with MALT lymphomas should be evaluated in a similar manner to individuals with nodal lymphomas, the more common type of lymphoma that originates at sites within the lymphoid system.

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Q: What is the best staging area for the evaluation of patients with MALT lymphomas?
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What has been the stumbling block in determining the optimal treatment for MALT lymphoma?

While the outlook for patients with MALT lymphomas is good, difficulties in diagnosis and staging have left the optimal treatment a matter of continued study.


What individuals may be at increased risk to develop MALT lymphomas?

In some cases, such as in the thyroid, MALT lymphomas seem to arise in patients who have autoimmune diseases, which make their immune systems treat their own tissue as foreign or antigenic.


What portion of US patients with H.pylori infections develop MALT lymphomas?

In the United States, where infections with H. pylori are quite common, less than 1 in 30,000 people who have H. pylori in their stomachs develop MALT lymphomas.


What is the typical prognosis for MALT lymphoma?

In general, the prognosis for patients with MALT lymphomas is good, with overall five-year survival rates that are greater than 80%.


What symptoms are associated with MALT lymphomas?

MALT lymphomas are generally indolent, that is, they grow slowly and cause little in the way of symptoms.


What causes MALT lymphomas outside the stomach?

It is not known if infectious agents also cause MALT lymphomas outside of the stomach.


How are MALT lymphomas recognized in an endoscopy examination of the stomach?

MALT lymphomas are then recognized as areas of inflammation or ulceration within the stomach.


When are early diagnoses of MALT lymphoma usually made?

The indolent nature of most MALT lymphomas means that the majority of patients are diagnosed at early stages with relatively nonspecific symptoms.


What is the occurrence of MALT lymphomas in the general population?

MALT lymphomas occur at a frequency of about 1.5 per 100,000 people per year in the United States and account for about 10% of all non-Hodgkin's lymphomas.


What chances for recovery do those with MALT lymphomas outside the digestive tract have?

Overall these patients have five-year survival rates greater than 90%.


How are MALT lymphomas in the stomach treated?

Those MALT lymphomas that arise in the stomach in response to H. pylori infections are generally successfully treated with antibiotics, which eliminate the bacteria.


What is it essential for a pathologist to determine during evaluation of MALT lymphomas?

it is essential that the pathologist determine whether or not the lymphoma has grown beyond the borders of the mucosa, which lines the stomach or other gland.