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C3H4Cl2F2O

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Q: What is the chemical formula of methoxyflurane?
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How does methoxyflurane cause floride toxicity?

§ Methoxyflurane → methoxydifluoroacetic acid (MDFA) <chlorination> § Methoxyflurane → fluoride + dichloroacetic acid <O-demethylation> § MDFA degrades to fluoride § Experiments have shown that it is probably the combination of fluoride and dichloroacetic acid which causes nephrotoxicity.


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