That would actually be dependent on the make and model of the truck, not the engine. Even if it was dependent on the engine, you never specified if it was the ISX12 or ISX15.
15 gallons
The Cummins ISX uses red ELC (extended life coolant).
Isx is 45 qts with a new filter
Red ELC.
11 gal
Broken head gasket...since an ISX with 200 miles is still under warranty, let Cummins fix it.
Red ELC.
~11 gallons, including the filter.
Head gasket & oil cooler
Head gasket & oil cooler
How to remove turbo on 200 cummins ISX
The Cummins ISX is a family of post-ACERT heavy duty diesel engines.