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What is the difference between amyloid beta protein and tau protein?
Mindmystery
== == Amyloid beta (AB) protein is produced from the cleavage of amyloid precursor protein (APP: a transmembrane protein) by beta secretase and gamma secretase. The build up of this intact AB protein leads to formation of amyloid plaques. Tau is a group of microtubule associated proteins which contributes to the assembly and stabilization of microtubules in axons. However, hyperphosphorylation of tau leads to tau aggregation and formation of neurofibrillary tangles (NFT). Intracellular NFT and extracellular amyloid plaques are two pathological hallmarks of Alzheimer's disease.
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What is the difference between alpha carotene and beta carotene?
The difference is the position of the double bond
What is the difference between a beta plus particle and a beta minus particle?
The difference between a beta plus and beta minus particle is the electrical charge. The charges are equal, but opposite. The beta minus particle is an electron with a negative charge, while the beta plus particle is an anti-electron or positron with a positive charge.
What level of molecular organization is a beta-folded sheet?
A beta-folded sheet is a secondary structure of a protein, which is the next level of molecular organization above the primary structure. It is formed by hydrogen bonding between adjacent segments of a polypeptide chain, creating a flat and elongated sheet-like structure.
What is the difference between alpha DC and beta DC?
alpha dc = beta dc/(beta dc +1) alpha dc is typically 0.95 to 0.99 but is always less than 1 beta dc is typically 20 to 200 but can vary
The alpha helix and beta pleated sheet represent which level of protein structure?
The alpha helix and beta sheets are found at the Secondary level of protein folding. It's when the protein is taking its shape. Secondary structure
Why does tau overexpression and deposits of amyloid beta protein inside and between neurons cause the neurons to die?
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What is protein type AAA?
AmyloidosisIn medicine, amyloidosis refers to a variety of conditions in which amyloid proteins are abnormally deposited in organs and/or tissues. A protein is described as being amyloid if, due to an alteration in its secondary structure, it takes on a particular aggregated insoluble form similar to the beta-pleated sheet. Symptoms vary widely depending upon the site of amyloid deposition. Amyloidosis may be inherited or acquired.(Extracted from Wikipedia.)
What causes the hereditary form of CAA?
In hereditary CAA, genetic defects, typically on chromosome 21, allow accumulation of amyloid, a protein made up of units called beta-pleated sheet fibrils. The fibrils tend to clump together, so that the amyloid cannot be dissolved.
Alzheimer's disease is most closely linked to the loss of neurons that produce?
its a chemical inbalance that doesnt let oxygen flow right to the areas that it needs to pretty much in elderly people this happends alot the lost memory, they sometimes dont remember names but they could at times recognize voices i work in a nursing home n i see alot of this situations they could remember one day the next u dont even exist i just hope that god helps the same way i help them
Difference between beta and standard deviation?
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What is plaque on the brain?
Do you mean brain plaque? Amyloid plaques in the brain generally are found in people who suffer from Alzheimer's disease. According to RxList.com, these plaques are bunches of beta amyloid protein and small fragments of neurons. The plaques float in the tissue that surrounds and lies between nerve cells. As yet, scientists are not clear about whether these plaques are side effects of Alzheimer's or may be harmful themselves. Brain Plague is a science fiction book.
Why does Presenilin cause Alzheimers?
Familial AD cases associated with presenilin mutations only account for a small proportion of AD cases. The physiological roles of presenilins are diverse and not completely understood. However, they play a role in the metabolism of the amyloid precursor protein (APP). Presenilin mutants are thought to decrease the metabolism of APP, but increase the proportion of specific amyloid beta (1-42) and truncated amyloid beta (x-42) alloforms. These types of proteins are prone to aggregate with one another, and form plaques (i.e., a common neurological hallmark of Alzheimer's disease). The pathological role of plaques and the intermediate stages in their formation is debated, however research suggests that smaller and more soluble amyloid beta aggregates are potent neurotoxins which may cause the initial stages of synaptic deterioration in disease.
What is the difference between Gamma and Beta burns?
"beta burns" are shallow surface burns
What is the difference between beta cells and acinar cells?
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What is the difference between alpha carotene and beta carotene?
The difference is the position of the double bond
What is the difference between a beta plus particle and a beta minus particle?
The difference between a beta plus and beta minus particle is the electrical charge. The charges are equal, but opposite. The beta minus particle is an electron with a negative charge, while the beta plus particle is an anti-electron or positron with a positive charge.
What is the difference between halo reach beta and the actual game on xbox live?
The Beta was used to test the game for Bungie.
