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What is the difference between confirmation and configuration?
Wiki User
∙ 13y ago
Conformation is the spatial arrangement of atoms in a molecule that can come about through free rotation of atoms about a single chemical bond. It can be changed without breaking bonds. Example. rotation about single bonds produce the cis-trans, and E-Z conformations
especially of organic molecules.
(Think: Conformation: orbiting)
On the contrary, configuration is permanent geometry. It refers to spatial arrangement of bonds and can be changed only by breaking bonds. Example: L- & D and R- & S- configurations of organic molecules can only be changed by breaking one or more bonds
connecting the chiral atom.
(Think: Con-"fig": breaking a twig)
Wiki User
∙ 13y ago
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