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seroquel XR (eXtender Release) can be taken just one-dose daily; usually 3 hours before bed-time without food or a light-meal. Seroquel immediate release should be taken 2 or 3 times daily. Seroquel XR reduce extrapiramidal symptoms, and common side effects like weight gain with 2-3 times administration (Max. concentration are not so high with XR version)

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Q: What is the difference between seroquel and seroquel XL?
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