Roughly 265 miles, and you really should be using Google Maps to answer these questions. Just go there and type in "Los Angeles to Las Vegas" (if you're using more obscure cities, you may want to add the state also, but in general it's pretty good about guessing that you probably meant Manhattan, NY and not Manhattan, KS) and it will not only give you the road distance, it'll tell you what particular route it chose and may also list alternative routes if there are multiple options that are about equally good. I've put a link in the related links section.
The driving distance from Las Vegas, NV, USA to Los Angeles, CA, USA is 270.71mi / 435.66km
The driving distance from Las Vegas, Nevada to Los Angeles, California is 270 miles.
The Driving distance from Los Angeles to San Francisco is further. The driving distance to Las Vegas, NV is 270 miles per Map Quest. The driving distance to San Francisco, CA is 382 miles per Map Quest.
Los Angeles to Las Vegas
The driving distance from LAX to Las Vegas is 287 miles.
The driving distance from Las Vegas, Nevada to Zion, Illinois is 1,771 miles.
What is the distance in driving miles from Flagstaff to Las Vegas?
The driving distance from Riverside, California to Las Vegas, Nevada is 238 miles.
The driving distance from Glorieta, New Mexico to Las Vegas, Nevada is about 645 miles.
It is 266 miles according to Google Maps.
The driving distance from Mainland, Pennsylvania to Las Vegas, Nevada is about 2,485 miles.
The driving distance between San Diego and Las Vegas is 332 miles.