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How do DNA probes work?

Updated: 8/11/2023
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10y ago

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These are the tiny fragments of single stranded DNA which are labelled with radioactive materials or fluorescing material with base pairs complementary to the fragments of the VNTR regions of a DNA. These are used during electrophoresis or DNA fingerprinting in order to get the position of desired DNA.

For example; a VNTR region has base pair ATG, then the probe has got the base pairs TAC and a radiactive isotope, like P32 is attached to it. Now the probe combines only to those places where there are the VNTR regions. The isotope will now radiate and so the places from where radiations are received only contain the VNTRs. Hence we can specify the region.

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12y ago
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10y ago

DNA probes are tiny little fragments of DNA which have been labeled with radioactive materials with base pairs complementary to the fragments of the VNTR regions of a DNA.These have been used during an electrophoresis or DNA fingerprinting in order to get the position of a certain DNA profile.

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11y ago

Working with Dna is all about complementary biochemical arrangements. While the Dna 'molecule' has several gazzillion positively unique fingerprints, the Probe contains a short, highly specific sequence that will bind in the fashion of Complementarity to just only that one specific area of the Dna that it is complementary to or with.

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10y ago

They transfer the DNA from the bacteria onto filter paper. The clone cells bearing the donor DNA as well as the attached probe glow when they are placed under ultraviolet light or exposed to photgraphic film. This reveals its location, and scientists can now grow more of the specific recombinant bacterial clone.

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They are complimentary sequences designed to target a specific sequence and signal their location in some way, either by attaching a radioactive part to the probe or something that emits light once it's bonded to the targeted DNA.

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11y ago

used for the dissection of frogs or animals

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12y ago

A DNA probe is used to find a sequence of nucleotides in a segment of DNA.

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