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What breaks down acetylcholine?
Acetylcholinesterase
What is acetylcholinesterace?
Acetylcholinesterase, also known as AChE, is an enzyme which is critical to the function of animals from ants to elephants. This enzyme's sole responsibility is to break down the neurotransmitter acetylcholine. Acetylcholine sends messages between nerves, signaling muscle contractions. If the neurotransmitter was not broken down after it had served its function, the muscle involved would not be able to relax, and this could create spasms, paralysis, and other problems.
What systems do nerve agents affect?
Nerve agents typically affect the acetylcholine system by irreversibly binding to the enzyme, acetylcholinesterase. This prevents the body from catabolizing acetylcholine, resulting in an accumulation of the neurotransmitter in the synapse and neuromuscular junction.
Mechanism of action of carbamate poisoning?
they inactivate the acetylcholinesterase enzyme which is necessary to break up Ach into acetate and choline,thereby causing increase in synaptic Ach leading to anticholinesterase poisoning...example neostigmine,physostigmine,edrophonium, etc
High enzyme kcat means low Km?
Not necessarily. You could have a relatively high Kcat but a moderate Km value. This is of course relative to all enzymes across the board. An example would be to compare catalase and acetylcholinesterase. Catalase has a Km of 1.1M but a Kcat of 4 X 10*7 while acetylcholinesterase has a Km of 9 X 10*-5 but a Kcat value of only 1.4 X 10*4. While a low Km value will definitely mean a high affinity of enzyme for substrate, this does not readily eqaute to a high Kcat value.
What is an antiacetylcholinesterase?
It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters.
Is there a sentence which includes the word acetylcholinesterase if so what is it?
"Acetylcholinesterase" production results in the production of a glucosteroid inhibitor.
What destroys ACh?
Acetylcholinesterase
What agent inhibits Acetylcholinesterase?
neostigmine
What breaks down acetylcholine?
Acetylcholinesterase
How is acetylcholine (ACh) removed from the synaptic cleft?
Acetylcholine is degraded by acetylcholinesterase
What is the medical abbreviation meaning Acetylcholinesterase?
ACHe
How is acetylcholinesterase dangerous to humans?
Acetylcholinesterase is dangerous to humans as it attacks nerves and causes a loss of use in the affected area. Poisons and venoms contain these properties.
What type of cbrne agent acts by inhibiting a cruicial enzyme called acetylcholinesterase?
Nerve agents are compounds that have the capacity to inactivate the enzyme acetylcholinesterase (AChE)
What has the author John A Montgomery written?
John A. Montgomery has written: 'Standard operating procedures for the determination of acetylcholinesterase activity' -- subject(s): Pesticides, Acetylcholinesterase, Toxicology
What kind of enzyme breaks down acetylcholine?
Acetylcholinesterase
What enzyme is responsible for skeletal muscle relaxation?
acetylcholinesterase
