What is the meaning of wire in the blood?

Answer 1

All I could find on it is that it is a UK TV show.

It is a line from T.S. Elliot's "Four Quartets". - "The trilling wire in the blood/sings below inveterate scars/appeasing long-forgotten wars."

Taken to mean an adrenalin rush though Elliot never claimed this to be the case. Has possibly some drug reference for example the injection of a needle.

In an interview Robson Green said the phrase "wire in the blood" was taken to mean a genetic kink, something impure and unusual in the blood, that leads to the kind of psychosis Dr Hill might deal with.