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Q: What is the method of action of nucleoside analogs?
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What is the mode of action of nucleoside and nucleotide analogs?

Nucleoside and nucleotide analogs inhibit viral replication by incorporating into the viral genome during replication. These analogs lack the necessary functional groups for further elongation of the viral genome, leading to termination of viral replication and inhibition of viral protein synthesis. This disruption ultimately stops the virus from spreading and replicating.


Are nucleoside analogs that inhibit DNA synthesis effective against viral diseases?

yes, nucleoside analogues are artificial nucleosides. The block the completion of new viral DNA chains, therefore, preventing the production of new viral bodies. This way the viral enzyme, reverse transcriptase is more likely to incorporate the nucleoside analogue into the DNA than the host's DNA polymerase.


Difference between nucleoside reverse trancriptase inhibitor and non nucleoside reverse transcriptase inhibitor?

They have a different mode of action in inhibiting the transcription of the viral DNA. The NRTI is actually a nucleoside that incorporates into the viral DNA but it does not have a 3-hydroxyl group so it inhibits and halts the continued growth of the viral DNA chain. The NNRTI's bind to the reverse transcriptase and inhibit its movement.


What type of drug is acyclovir?

Guanine nucleoside analogues, Nucleoside analogues and Antiviral drugs


How many nucleotids are in a double helix?

The number of nucleotides (and base pairs) varies from species to species. However, the number of DIFFERENT nucleotides is 4: - adenine nucleoside phosphate - cytosine nucleoside phosphate - guanine nucleoside phosphate - thymine nucleoside phosphate


What is endogenous purine nucleoside?

A dog


What is included in corticosteroids?

These analogs include glucocorticoids, which are anti-inflammatory agents with a large number of other functions; mineralocorticoids, which control salt and water balance primarily through action on the kidneys; and corticotropins.


Why can't the human immune system eliminate herpes viruses from neurons?

Current first line treatments for HSV-1 (Herpes Simplex Virus type I, usually in the mouth region) and HSV-2 (Herpes Simplex Virus type II, usually in the genital region) are Acyclovir, Valacyclovir and Famcicolovir. These drugs are nucleoside analogs. Their method of action is to prevent the production or new viral genetic material by inserting themselves into the viral DNA and terminating synthesis. Therefore, they are only functional against stopping the production of new viruses. These drugs cannot kill existing viruses lying dormant in the neuron. Currently no drug exists to kill dormant (non-replicating) HSV-1 or HSV-2 in the body.


The components of a nucleoside are?

The components of a nucleoside are: A pentose sugar(generally ribose or deoxyribose), and a nitrogenous base which may be Adenine/Guanine/Thymine/Cytosine/Uracil. It becomes a nucleotide on addition of a phosphate group.


Organic compounds which are sulfur analogs of alcohols are referred to as?

Thiols


What does NTP stand for?

Nucleoside triphosphate. Network Time Protocol Notice To Proceed


What is the dispersal method of balsam?

Explosive or splitting action