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MHC is important in adaptive immunity. It provides your adaptive immunity, T cells, processed antigens so that it can decide whether what your cell has is a foreign substance that needs to be destroyed or if it is self that needs to be left alone.
MHC is to present on a cell's surface for your T cells and antibodies to determine if it is self or foreign.
They are all players of your adaptive immunity.
No, it's cellulair. Handy to be recognized by the cytotoxic T-cells.
The advantage of having a highly polymorphic MHC is that it adds to variety of which it can bind to a peptide. If MHC cannot bind to a viral or bacterial peptide then your body cannot use its' adaptive immunity to fight off an infection. The T cell requires MHC to activate and if MHC is not binding to anything because it has such a small repertoire of alleles to create a MHC molecule, it will render T cells useless. So to have a highly polymorphic MHC gene that can encode to bind to many different peptides is advantageous for survival.
The role of cytotoxic T cells is to alert Class I MHC molecules to a foreign antigen. This is achieved by the foreign antigen associating with the MHC molecule and being moved out to the cell surface, where the cytotoxic T cell alerts the MHC molecule of the infection.
MHC doesn't "recognize" bacteria or anything. It's job is simply take up the broken peptides. These peptides can be originally from a virus, bacteria, or from the cell itself (self). It will take these antigen that it can bind to and bring it to the cells surface. Your adaptive immunity cells (B and T cells) job is to "see" what the MHC has to offer and identify it as self (leave alone) or as foreign (need to destroy).
Humoral Immunity- acquired immunity in which the role of circulating antibodies is predominant. Natural Immunity- the resistance of the normal animal to infection
MHC IMHC I is present in all cells except red blood cells (they lack nuclei). MHC I will present an intravesicular antigen to the cells surface for it to be identified as self or foreign by your adaptive immunity cells.MHC IIMHC II is present in professional antigen presenting cells which include: macrophages, B cells and dendritic cells. These cells will engulf bacteria, soluble proteins, viruses, etc. Whatever was taken into the cell becomes processed in the increasingly acidic endosome that eventually will cut the antigen into peptides. MHC II transported from the ER will meet up with this endosome and the peptides will bind to MHC II for it to eventually present on the cells surface.
no
MHC = major histocompatibility complex What makes up MHC are HLA's (human leukocyte antigens), which there are subclasses for.
MHC Krylya Sovetov was created in 2008.