pKa (dissociation constant) is variable with temperature.
pKa = -log KapKa = -log 5.4x10^-10pKa = 9.27
How can you calculate pka valve if ph is given?
All you need to do to get Ka is to take the antilog of the pKa.
By following + or - 2 pH to the pKa value
Generally pediatric administration of drotaverine is not recommended by most of pharma companies. LUCKY...
drotaverine is soluble in methanol, tetra hydro furan, dichloro methane and ammonium acetate buffer (0.01 M, pH=5)
pKa=40
how do you calculate pKa
pKa=2.86
pKa = 15
It is around pKa=13
Doxofylline Pka value is about 9.8.
pKa (dissociation constant) is variable with temperature.
The pka of a protonated ether (the conjugate acid) is about -3.5
The pKa of sulfonic acid is < 0
pKa of methanol is 15.5 see this pdf for more information about pka-values: http://chemweb.unp.ac.za/chemistry/Physical_Data/pKa_compilation.pdf