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Here are some natural anti-coagulants:

1. Protein C and protein S

Activated protein C and protein S can digest factors Va and VIIIa.


2. Antithrombin III

Antithrombin III is a circulating protease which blocks the activity of thrombin (factor II) as well as some other clotting factors. Antithrombin III is faciliated by heparin, a substance present in the plasma and on the surface of endothelial cells.


3. Tissue factor pathway inhibitors

They are secreted by endothelial cells. These inhibitors bind to tissue factor/factor VIIA complexes. They inhibit the ability to produce factor Xa and the subsequent formation of thrombin.


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7y ago
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11y ago

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Q: What is your body's natural anticoagulant?
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