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There is an infection of some kind, probably would have gotten in through a scratch or a thorn in the kitten's leg. If there is so much pus and inflammation that the whole leg is swollen, you need to get the kitten to a vet immediately as an infection this severe is endangering its life. It will need antibiotics, and if the infection is very bad it may even need to stay at the vet's.

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Q: What makes a little kittens leg swell up with pus?
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