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Thrombolytic is the general term for the class of drugs used to dissolve blood clots. Clots (thrombi) can reduce or interrupt blood flow by blocking the vessel which can result in injury to the tissues that are deprived of the blood flow and oxygenation. This occurs sometimes in a "heart attack" when blood flow is restricted by a clot, and damage or death (infarction), of the tissue of the myocardium (heart muscle) results.

A common thrombolytic agent which is used for this purpose in emergency medicine measures for conditions like blood clots in the brain (cerebral thrombosis/embolus) or a coronary artery thrombosis/embolus that is causing or threatening a myocardial infarction is called TPA. TPA stands for Tissue Plasminogen Activator (also abbreviated PLAT). It acts as an enzyme to break down blood clots. Sometimes thrombolytic agents ("clot busters"/"clot busting medicines") such as Streptokinase or Urokinase are necessary to dissolve blood clots.

A related class of drugs is called anticoagulants, but rather than quickly dissolving clots like thrombolytics do, these "blood thinners," as they are sometimes called, act to prevent clot formation instead. They are used either as short term or long term medications. Examples of some of the more common anticoagulants are heparin, Coumadin, and Lovenox.

Thrombolytic drugs include:

  • tissue plasminogen activator t-PA:
  • alteplase (Activase)
  • reteplase (Retavase)
  • tenecteplase (TNKase)
  • anistreplase (Eminase)
  • streptokinase (Kabikinase, Streptase)
  • urokinase (Abbokinase)

Among those, commonly used drugs are alteplase, reteplase and streptokinase.

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11y ago
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7y ago

tPA is often used to dissolve blood clots. The only FDA approved treatment for ischemic strokes is tissue plasminogen activator (tPA). tPA works by dissolving the clot and improving blood flow to the part of the brain being deprived of blood flow. If administered within 3 hours- 4.5 hours, tPA may improve the chances of recovering from a stroke.

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11y ago

Thrombolytic means clot-dissolving.

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10y ago

heparin

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Q: What medicine is used to dissolve blood clots?
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It is a Thromolytic used to dissolve blood clots to revive patients during a heart attack. It is the commercial name given to Streptokinase.


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